Mature, functional human iPSC-derived cells within days, powered by opti-ox™
The future of human health will be defined by technologies that accelerate the world's access to more effective medicines.
Human cells are a cornerstone of fundamental disease research, drug discovery, and clinical translation. Yet, despite decades of research into iPSCs, emerging cures for some of the world’s most pervasive diseases have been bottlenecked by a lack of access to standardised, easy to use and readily accessible human cells.
We built ioCells to solve this challenge.
Developed on our platform, and powered by opti-ox technology, ioCells are human cells precision reprogrammed from iPSCs consistently, at scale. With ioCells, scientists no longer need to battle with variance, unreliability, physiological irrelevance and long experimental timelines. Instead, scientists can finally focus on the next great advances in human health.
ioCells are for research use only.
Browse ioCells portfolio
ioWild Type Cells™
ioWild Type Cells are defined, easy-to-use, functional iPSC-derived human cells from a healthy donor background that are ready for fundamental research and drug discovery experimentation within days.
ioDisease Model Cells are ioWild Type Cells engineered to contain disease-relevant mutations. ioDisease Model Cells and ioWild Type Cells form an isogenic pair allowing scientists to make true comparisons.
Our platform ensures consistency between every batch of cells, overcoming the challenge of data reproducibility.
ioCells generate quality data at industry leading seeding densities. You can do more with every vial as every well saves you money.
Every ioCell has its identity characterised by ICC, RT-qPCR and RNA-Seq at minimum.
ioCells are delivered cryopreserved and require a simple protocol using an open-source medium to get started.
Precision reprogrammed cells mature rapidly, meaning cells are ready for experimentation and data gathering within days post-revival.
With opti-ox technology we can make billions of consistently reprogrammed cells, surpassing the demands of industrial workflows.
Our precision cellular reprogramming technology
Every ioCell is powered by opti-ox.
With opti-ox, we take inducible genetic programs that are coded to define cell fate, and integrate them into regions of the genome that are not affected by gene silencing. This precise control drives a programmed identity in every cell, and means human iPSCs can be reprogrammed into any cell type.
Each vial of ioCells contains a defined and known cell identity and purity. Consistency between batches eliminates the need to re-validate for every experiment. As a result, ioCells are ready for quality data production in a matter of days.