Development of human iPSC-derived hepatocytes for drug discovery, translational research and toxicity testing

You will learn:

• ioHepatocytes provide a scalable alternative to primary human hepatocytes, displaying classic cobblestone morphology and expressing key markers like ALB and HNF4A with high lot-to-lot consistency

• ioHepatocytes Discovery Research demonstrate essential metabolic functions such as glycogen storage, lipid accumulation, and bile canaliculi formation for disease modelling

• Advanced toxicology applications are supported by ioHepatocytes Toxicology, which express phase I–III drug metabolism genes and functional CYP450 enzymes, matching the toxic response of primary cells for predictive safety testing