Depletion of Intracellular Glutamine Pools Triggers Toxoplasma gondii Stage Conversion in Human Glutamatergic Neurons
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Depletion of Intracellular Glutamine Pools Triggers Toxoplasma gondii Stage Conversion in Human Glutamatergic Neurons

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Read the publication to explore:

  • Mechanisms of Toxoplasma gondii cyst formation in human neurons, driven by abnormal host glutamine metabolism

  • The dual impact of IFN-γ stimulation and infection-mediated inhibition of glutamine transporters (SLC38A1/SLC38A2)

  • The conservation of these stage conversion mechanisms in human iPSC-derived glutamatergic neurons

  • How ioGlutamatergic Neurons were used
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Bando, et al
Frontiers in Cellular and Infection Microbiology

2022

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