Publication
Treatment of spinal injury muscle spasticity by spinal subpial AAV9-GAD65/VGAT delivery: An efficacy and safety study in rat, pig, and NHP
Read publicationRead the publication to explore:
- How subpial segment-targeted delivery of GAD65 and VGAT transgenes suppressed spinal injury-induced muscle spasticity in rats
- Restored inhibitory GABAergic tone, shown by increased protein levels in excitatory VGLUT2 terminals
- How ioGlutamatergic Neurons were used
Nguyen D, et al.
Molecular Therapy
2026