Interferon-γ exposure of human iPSC-derived neurons alters major histocompatibility complex I and synapsin protein expression
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Interferon-γ exposure of human iPSC-derived neurons alters major histocompatibility complex I and synapsin protein expression

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Read the publication to explore:

  • The impact of acute interferon-γ (IFNγ) exposure on the development of immature human glutamatergic neurons

  • Molecular alterations including STAT1 pathway activation and the upregulation of MHCI and Complement component 4A (C4A)

  • Evidence of synaptic disruption characterised by decreased synapsin I/II protein levels during early neuronal development

  • How ioGlutamatergic Neurons were used
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Pavinlek, et al
Frontiers in Psychiatry

2022

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