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A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth
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The development and optimisation of 3D human corticospinal motor organoids
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How single-cell transcriptomics, computational analyses, axon regrowth assays, and live imaging identified transcriptional alterations contributing to decreased axon growth in maturing human cortical neurons
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How targeting the restrictive neuronal program reverses the human cortical axon repair block and how cortical axon repair enhancers can be identified with a target-informed drug screening
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How ioSkeletal Myocytes were used
Gibbons G, et al.
Cell Reports
2026