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Neuroinflammation demonstrated by 11C-ER176 PET with amyloid and tau pathology
Publication

Neuroinflammation demonstrated by 11C-ER176 PET with amyloid and tau pathology

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Read the publication to explore:

  • How translocator protein (TSPO) was upregulated in human microglia under Alzheimer’s disease (AD)-like inflammatory conditions

  • How neuroinflammation, measured by 11C-ER176 TSPO PET, increased in cognitively unimpaired amyloid-positive participants and became more widespread with increasing disease severity

  • How associations between neuroinflammation and tau pathology were particularly extensive in temporal and parietal regions

  • How ioMicroglia were used

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Kandimalla M, et al.

Alzheimer’s & Dementia

2026

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