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AGC kinase homology requires and enables co-targeting for CNS regeneration
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How co-inhibiting AGC family kinases is needed for optimal neurite outgrowth in rodent and human neurons
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How the shared structure of these kinases allows a single molecule to target them all
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The optimisation of TMP-316, a drug candidate that produced lasting motor recovery in rats after spinal cord injury
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How ioGlutamatergic Neurons were used
Al-Ali H, et al.
bioRxiv | Preprint
2026