Human iPSC-derived Gaucher and Parkinson’s disease model
ioGlutamatergic Neurons GBA null/WT are opti‑ox™ precision reprogrammed glutamatergic neurons carrying a genetically engineered heterozygous knockout of the GBA gene encoding the glucocerebrosidase (GCase) enzyme. The cells offer a suitable model to study the molecular and cellular processes seen in Gaucher and Parkinson’s diseases.
Related disease model cells are coming soon with a heterozygous PRKN R275W or a homozygous PRKN R275W mutation. All can be used alongside their genetically matched control, ioGlutamatergic Neurons™.
Register your interest, and we will notify you as soon as the product is available.