Hear what scientists have to say about ioCells
Dr Irit Reichenstein
Senior Scientist | Anima Biotech
"We did use the cells and were very happy with them :) They were very homogenous (unlike motor neurons from other vendors that we worked with), viable and absolutely beautiful. We got wonderful results with them."
Dr Mariangela Iovino
Senior Group Leader | Biology Discovery | Charles River
“Our major surprise when we first used the ioGlutamatergic Neurons was that after thawing the cells in 384-well format, we could see immediately after 2 days a nice neuronal network, and there was no well to well variability within the same plate. This made our assay quite robust.”
Dr Elizabeth Di Lullo
Associate Scientific Director | Brainever
“We thawed the cells and they looked wonderful. Close to 100% viable and looked great in cell culture! No clumping and easy to culture.”
Amy Rochford
PhD Neural Engineering and Bioelectronics | Cambridge University
"The ioSkeletal Myocytes have a much shorter cell culture time compared to harvesting primary muscle cells, saving us months on cell culture work. Another advantage of these cells is their higher population purity compared to other stem cell derived cells. This enables us to achieve higher numbers of functional striated muscle that are capable of contracting under electrical stimulation. "
Dr Shushant Jain
Group Leader | In Vitro Biology | Charles River, 2021
"These cells enable us to move rapidly as from the moment of plating within 4-7 days we have mature and functional neurons."
Dr Koby Baranes
Research Associate | University of Cambridge
"These cells provide a reliable and pure source of glutamatergic neurons, resembling primary human ones. They are ready-to-use which makes it much more easy for tissue culture work and for reproducible results.”
Dr Simone Mader
Junior Group Leader | Institute of Clinical Neuroimmunology | LMU Munich
"bit.bio’s ioGlutamatergic Neurons provide a human model that is well-characterised, batch-consistent, and easy to use with our limited neuronal culture experience. We are grateful for the support from the bit.bio team and are now preparing our data for publication."
Rodney A. Bowling Jr., Ph.D.
Co-Founder & Chief Scientific Officer | Everlum Bio
"These neurons are 90% GABAergic and do undergo gymnosis. They also go from plating to experiment in 3 weeks, I couldn't be happier"
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Dr Ryan Jones
Postdoctoral Research Associate | Cardiff University
"We are using ioSensory Neurons to generate nerve bone interfaces to study pain in orthopaedic conditions like osteoarthritis, non-healing fractures and osteoporosis. Previously, using directed differentiation of iPSC-derived sensory neurons was incredibly time consuming and difficult. bit.bio’s cells rapidly produce a remarkable stable and robust phenotype and are invaluable to our research."
See how ioCells can benefit your research
Quick
Save months of work with cells that are ready-for-experiments within days
Ease-of-use
ioCells are delivered cryopreserved and have established protocols for experimental assays
Consistency
Unprecedented lot-to-lot consistency supports reproducible results
Human functional data
Physiologically relevant cells to generate translational data
Routine gene knockouts, activation and interference
CRISPR-Ready ioCells for easy gene perturbation experiments
Co-culture compatible
Build complex multi-cell cultures to model the CNS
Browse ioCells portfolio
ioWild Type Cells
ioWild Type Cells are defined, easy-to-use, functional iPSC-derived human cells from a healthy donor background that are ready for fundamental research and drug discovery experimentation within days.
ioDisease Model Cells
ioDisease Model Cells are ioWild Type Cells engineered to contain disease-relevant mutations. ioDisease Model Cells and ioWild Type Cells form an isogenic pair allowing scientists to make true comparisons.
CRISPR-Ready ioCells
CRISPR-Ready ioCells are human iPSC-derived cells constitutively expressing Cas9 nuclease for rapid gene knockout generation.
ioTracker Cells
ioTracker Cells are human iPSC-derived cells constitutively expressing a fluorescent protein for easy visualisation, tracking, and isolation of human cells in live-cell imaging assays.