Tau aggregate replication occurs at the pre-synapse of cultured human neurons and increases with application of TNFɑ
Publication

Tau aggregate replication occurs at the pre-synapse of cultured human neurons and increases with application of TNFɑ

Read publication

Read the publication to explore:

  • The use of neurons treated with TNFɑ to study tau aggregation at synapses

  • Findings showing that TNFɑ-driven tau aggregation occurs preferentially at the pre-synapse, forming predominantly non-fibrillar aggregates

  • Findings showing that tau aggregate replication is the dominant process and is faster than de-novo aggregate formation

  • How ioGlutamatergic Neurons were used

Read publication

Kedia S, et al.

bioRXiv

2026

Related pages

Products Learn about our range of human iPSC-derived cells for research and drug discovery
Our platform Discover the cell coding platform behind our cells
Contact us Talk to us to learn more about our team and products