28.06.2021 | Published by Bioinformatics
“For us, the DNA in the nucleus of a cell is a bit like the hard drive, so all the information is stored, it's actually read-only memory. And then, within a cell, only part of the operating system, part of these programmes that are stored on the DNA level are actually active. This is structured in what's called gene regulatory networks. And these are the sub-programmes in the cell. So genes that control these programmes are called transcription factors. What we do is we activate these transcription factors to instruct the cells and obtain certain functions. And what you can do is you can take this approach, and you can literally program a stem cell to become the cell type that you're interested in. And this is 10 times faster, we can do it with extreme precision. And it's very, very scalable .”
Mark Kotter
Founder and CEO bit.bio
The Bioinformatics CRO Podcast 2021