Our mission

Coding cells for novel cures

bit.bio_ioskeletal myocytes About us bit.bio-lab-image-3-opt
bit.bio-lab-image-3-opt bit.bio_ioskeletal myocytes About us

What we do

bit.bio is a synthetic biology company providing human cells for research, drug discovery and cell therapy. The company applies a patented safe harbour gene-targeting approach (opti-ox™; Pawlowski 2017) to inducibly express transcription factor combinations that reprogram human induced pluripotent stem cells (iPSCs) into highly defined and mature human cell types. 

The required transcription factor combinations are discovered using high throughput screens and advanced data analysis (bit.bio discovery platform). The company is currently marketing a wide range of cells and disease models for research and drug discovery under its ioCells brand including nerve cells, immune cells and muscle cells. 

The company was spun out of the University of Cambridge in 2016 and has since raised approximately $225M from leading investors, including Arch Venture, Blueyard Capital, Charles River Laboratories, Foresite Capital, M&G, Milky Way, National Resilience, and Tencent.

bit.bio-lab-image-4-opt bit.bio_ioGlutamatergic Neurons About us
bit.bio_ioGlutamatergic Neurons About us bit.bio-lab-image-4-opt

The company has expertise in the underpinning science of synthetic biology and stem cells, manufacturing, and clinical translation. The board includes Founder Dr Mark Kotter, Interim CEO Przemek Obloj, and Dr Richard Klausner.

Watch our Vision Video

"Transforming Medicine: Synthetic Biology for Drug Discovery and Cell Therapies"

We're driven by a bold vision—Empowering biomedical innovation and a new generation of cures through precision-programmed human cells. At bit.bio, we're harnessing the power of synthetic biology for drug discovery and groundbreaking cell therapies. Our team thrives on a simple yet powerful mission: coding cells for novel cures. It's about reimagining what's possible by programming human cells to create transformative medicines. Watch the video to see how our leadership presented the vision of bit.bio.

 

Leadership

1PrzemekO-resized-Adjusted
Przemek Obloj
Interim CEO
Leadership team
Przemek Obloj
Interim CEO
1PrzemekO-resized-Adjusted

Przemek brings two decades of financial and investment experience focused on health, life sciences and technology across Europe and North America. Prior to joining bit.bio, he built two investment organisations, led growth and buyout transactions with combined equity investment of $5 billion and was involved in over a dozen successful exits. Most recently, he served as the Managing Partner and CIO at a Swiss family office. Prior to that, he was the Managing Director and Head of European Private Equity at PSP Investments, a C$250 billion Canadian pension manager. Earlier in his career, he worked at CVC Capital Partners, EQT, and McKinsey & Company.

Kathryn
Kathryn Corzo
President, bit.bio Therapeutics
Senior Leadership team
Kathryn Corzo
President, bit.bio Therapeutics
Kathryn
Kathryn has over 25 years experience in early and late drug development across multiple indications and platforms. She was partner at Takeda Ventures, Inc. and Head of Oncology Cell Therapy Development at Takeda Pharmaceuticals where she built capabilities and oversaw a cutting edge oncology cell therapy portfolio. Prior to that, she held several roles at Sanofi Genzyme and built a two decade career at Hoffman – La Roche, Roche Molecular Systems, Eli Lilly and Syndax, contributing to the approval of 6 new cancer therapies and expansion of multiple indications.
Bit-bio_headshots_Pic0080
Kam Dhaliwal
Business Development & Partnerships
Leadership team
Kam Dhaliwal
Business Development & Partnerships
Bit-bio_headshots_Pic0080
IMG_1598-1-1
Emma Pepperell
Commercial
Leadership team
Emma Pepperell
Commercial
IMG_1598-1-1
Emma Pepperell, VP Commercial, joined bit.bio in August 2024. She spent 10 years at abcam gaining extensive experience of a fast-growing products business, across Product Management, Marketing, Portfolio & Product Development and Sales functions, with prior experience in life science product distribution. Emma has a DPhil from University of Oxford, where she studied the regulation of stem cell engraftment.
Orlaith Greenan_headshot
Orlaith Greenan
Operations
Leadership team
Orlaith Greenan
Operations
Orlaith Greenan_headshot
Orlaith Greenan, VP of Operations at bit.bio, is a results-driven leader with over a decade leadership experience in Quality across drug development and biotechnology industries. She implements scalable strategies that optimise cost, accelerate time to market, and drive revenue growth by embedding quality into operations. Her expertise ensures high-performing products and efficient, commercially-focused execution.
Bit-bio_headshots_Pic0028
Thomas Moreau
Precision Reprogramming Research
Leadership team
Thomas Moreau
Precision Reprogramming Research
Bit-bio_headshots_Pic0028
Thomas Moreau is a biologist with over 20 years of experience in stem cell and life sciences. He joined bit.bio in 2018 from the University of Cambridge, where he pioneered forward cell programming approaches in Prof Roger Pedersen lab. He is a member of the RnD leadership team, leading cell programming research and innovation and technically supporting key partnerships with industry and academia.
Will Bernard 8
Will Bernard
Cell & Applications Development
Leadership team
Will Bernard
Cell & Applications Development
Will Bernard 8
Bit-bio_headshots_Pic0011
Oliver Dovey
Functional Genomics
Leadership team
Oliver Dovey
Functional Genomics
Bit-bio_headshots_Pic0011
Bitbio_Headshots_Oct22_Pic0021_1st
Ania Wilczynska
Bioinformatics & AI
Leadership team
Ania Wilczynska
Bioinformatics & AI
Bitbio_Headshots_Oct22_Pic0021_1st
Ania Wilczynska is Director of Bioinformatics and AI. Her team is focused on understanding the gene regulatory code that defines our ioCell products and employing cutting-edge AI and machine learning solutions to data analysis. She has over a decade of experience in Bioinformatics and Data Science and over two decades in molecular, developmental and cancer biology.  Prior to joining bit.bio in 2020, she held positions at the University of Cambridge, MRC Toxicology Unit and the CRUK Beatson Institute (now CRUK Scotland Institute).
bit-bio_headshotsMay22_Pic0008
Megan Doe
Business Finance & Strategy
Leadership team
Megan Doe
Business Finance & Strategy
bit-bio_headshotsMay22_Pic0008
Megan Doe, Ph.D., is Vice President of Business Finance and Strategy at bit.bio, where she leads investor relations and corporate communications, portfolio strategy, financial analytics, programme management, and business operations. She brings over a decade of experience in the biopharma industry, having worked at Sanofi, Takeda, and L.E.K. Consulting.
Sam Jones-headshot-Apr25
Sam Jones
Finance
Leadership team
Sam Jones
Finance
Sam Jones-headshot-Apr25
.
Kai Ling Gan-headshot
Kai Ling Gan
Legal
Leadership team
Kai Ling Gan
Legal
Kai Ling Gan-headshot

Board

1PrzemekO-resized-Adjusted
Przemek Obloj
Interim CEO
Board Member
Przemek Obloj
Interim CEO
1PrzemekO-resized-Adjusted

Przemek brings two decades of financial and investment experience focused on health, life sciences and technology across Europe and North America. Prior to joining bit.bio, he built two investment organisations, led growth and buyout transactions with combined equity investment of $5 billion and was involved in over a dozen successful exits. Most recently, he served as the Managing Partner and CIO at a Swiss family office. Prior to that, he was the Managing Director and Head of European Private Equity at PSP Investments, a C$250 billion Canadian pension manager. Earlier in his career, he worked at CVC Capital Partners, EQT, and McKinsey & Company.

Mark Kotter
Founder bit.bio
Board Member
Mark Kotter
Founder bit.bio
Mark is a stem cell biologist and neurosurgeon at the University of Cambridge. Aged nineteen, he decided to pursue a career in medicine to serve others and to make a difference in people’s lives. His curiosity led him down a path of clinical service and laboratory discovery. He became fascinated by synthetic biology, as he saw it as the key to a new generation of medicines. He is the founder of bit.bio and co-founder of the cultured meat start-up Meatable.
Cornel Chiriac -612x774
Cornel Chiriac
M&G Investments
Board Member
Cornel Chiriac
M&G Investments
Cornel Chiriac -612x774

Cornel Chiriac is an investment director with M&G Crossover Fund, focusing on late-stage investments in technology and science globally. He founded and invested for 10 years with 2050 Capital specialising in biotech and deep technology ventures. He also leads the Chicago Booth Angels Network in London and has extensive experience in strategy consulting at LEK Consulting.

Rick-Klausner-612x774
Richard D. Klausner
Altos Labs
Board Member
Richard D. Klausner
Altos Labs
Rick-Klausner-612x774

Dr Richard Klausner is the founder and chief scientist at Altos Labs and a visionary leader in biotechnology. He has co-founded several leading biotechnology companies, including GRAIL, Juno Therapeutics, and Lyell Immunopharma, and has held senior executive positions at Illumina and the Bill & Melinda Gates Foundation. As former director of the U.S. National Cancer Institute (NCI), he was instrumental in advancing CAR-T therapy and shaping the nation’s cancer research agenda

Jason Whitmire Photo
Jason Whitmire
BlueYard Capital
Board Member
Jason Whitmire
BlueYard Capital
Jason Whitmire Photo
Jason Whitmire is the Co-Founder and General Partner at BlueYard Capital, focusing on early-stage investments in transformative technologies. Previously, he was a General Partner at Earlybird and led Wind River Systems’ Linux business through its $1.2B acquisition by Intel Corporation. He has extensive experience in biotech, semiconductors, defense technologies and advanced energy, backing category-defining companies globally

Scientific advisory board

resized image (52)
Anil Dhawan
MBBS, MD, FRCPCH, King's College Hospital
Advisor
Anil Dhawan
MBBS, MD, FRCPCH, King's College Hospital
resized image (52)
Professor Anil Dhawan is a Consultant in Paediatric Hepatology at King’s College Hospital in London, UK, with a special interest in liver cell transplantation for liver-based metabolic defects and acute liver failure. Prof Dhawan is the Director of King’s Cell Therapy Unit. He is well known internationally and has held board-level appointments with the European Society of Paediatric Gastroenterology, Hepatology and Nutrition, International Liver Transplantation Society, and International Cell and Regenerative Society and Transplantation Society. He is also the Director of Research and Development, King’s College Hospital, London. He has 421 peer-reviewed publications, an H Index of 77 and over 22,000 citations.
Thore-Graepel-612x774-opt
Thore Graepel
Altos Labs
Advisor
Thore Graepel
Altos Labs
Thore-Graepel-612x774-opt
resized Katy Rezvani
Katy Rezvani
PhD, MD, The University of Texas MD Anderson Cancer Center
Advisor
Katy Rezvani
PhD, MD, The University of Texas MD Anderson Cancer Center
resized Katy Rezvani

Dr. Katy Rezvani is a Professor of Stem Cell Transplantation & Cellular Therapy at The University of Texas MD Anderson Cancer Center, where she serves as the Sally Cooper Murray Chair in Cancer Research, chief of the section for cellular therapy, director of translational research, and medical director of the GMP Facility. She also serves as executive director of MD Anderson's Adoptive Cell Therapy Platform. She leads a research lab with a focus on NK cell biology and developing novel NK cell engineering strategies for cancer, with the aim of translating these discoveries to the clinic. Dr. Rezvani completed her medical training at University College London, England and her PhD at Imperial College London. She completed her training in immunology and transplantation biology at the National Institutes of Health, Bethesda, MD. In addition, she has co-authored over 200 peer-reviewed publications and has received multiple prizes and awards.

resized Loïc Vincent
Loïc Vincent
PhD, Korro Bio
Advisor
Loïc Vincent
PhD, Korro Bio
resized Loïc Vincent
Loïc Vincent, PhD, is Chief Scientific Officer at Affini-T Therapeutics, an independent director of the Board of Directors at Alaya.bio, and a member of the Scientific Advisory Board at General Inception. He is an oncology scientist with more than 20 years of international experience in the academia/biotech/pharma industry, dedicated to advancing transformative therapies to patients suffering from cancer. Previously, Loïc was the Head of Takeda Oncology Drug Discovery Unit and Immunology Unit, responsible for building the Immuno-Oncology portfolio with a global network of outstanding biotech and academic collaborators, and for leading Takeda Cell Therapy Discovery. During his career, Loïc’s teams advanced more than 20 oncology drugs in the clinic based on various therapeutic modalities including small molecules, biologics, oncolytic viruses and cell therapies. Loïc is the author and co-author of more than 30 peer-reviewed publications, and more than 80 poster and oral presentations.
Marius Wernig
Marius Wernig
PhD, Stanford University
Advisor
Marius Wernig
PhD, Stanford University
Marius Wernig
Marius’ seminal 2010 paper in Nature demonstrating direct conversion of fibroblasts into neurons has sparked a widespread interest in cell reprogramming. He is the co-director of the Stanford Stem Cell Institute. His lab uses cellular reprogramming to understand how neurons are induced, and how they mature and maintain their identity.

Independent ethics and sustainability board

Enrica Alteri headshot about
Enrica Alteri
MD, DiplPharmMed, World Health Organization
Advisor
Enrica Alteri
MD, DiplPharmMed, World Health Organization
Enrica Alteri headshot about

After completing her medical studies in Rome and a post-doctoral fellowship focused on cellular immunology at the National Cancer Institute in Bethesda (USA), Dr Alteri spent 7 years in drug discovery and 5 years in clinical safety at Ciba-Geigy/Novartis in Basel. She was involved in major projects that yielded important drugs such as Gleevec for myeloid leukaemia, Coartem for malaria and Reyataz for HIV-AIDS. In 1998 she joined Serono in Geneva where she led the Pharmacovigilance and Risk Management team. At Serono, Dr Alteri was instrumental in establishing the company’s pharmacovigilance processes, as well as implementing the entire portfolio’s risk management strategy.
In 2012 she joined the European Medicines Agency, where she was Head of the Safety and Efficacy Sector for one year, being later promoted to Head of the Human Medicines Evaluation Division, and then to Head of the Human Medicines R&D Support Division.
She was member of the EMA Executive Board from 2013 until she retired in 2020.
In this roles, Dr Alteri was part of many high impact EMA’s initiatives, from the transparency of clinical trial data to the development of regulatory science strategy to 2025.
Dr Alteri has been consulting for the Swiss regulatory agency (Swissmedic), and is currently member of the Scientific Committee and faculty of the Master Course in Drug R&D of the University of Geneva. Dr Alteri regularly gives lectures on various aspects of R&D at the Universities of Rome, Cattolica and LUISS, and at the European Course in Pharmaceutical Medicine at the University of Basel. Moreover, she is member of the CIOMS Working Group XIII (Real World Data/Real World Evidence), and the CIOMS. Working Group Education. Most recently, she has been appointed as Core Member of the Proposal Review Committee of Unitaid for a 3-year period.

Marie-Claire Cordonier
Marie-Claire Cordonier Segger
PhD (Santa), DPhil (Oxon), MEM (Yale), LLB&BCL (McGill), BA Hons (Carl/UVic), FRSC, FRSA, WIJA, University of Cambridge
Advisor
Marie-Claire Cordonier Segger
PhD (Santa), DPhil (Oxon), MEM (Yale), LLB&BCL (McGill), BA Hons (Carl/UVic), FRSC, FRSA, WIJA, University of Cambridge
Marie-Claire Cordonier

Marie-Claire is a pioneering international expert in sustainability, law and public policy innovation. An award-winning expert jurist, executive and law professor specialised in corporate social responsibility, climate law and governance, sustainable trade and ethical investment rules, she is Visiting Chair of Sustainable Development Law and Policy at the University of Cambridge, and also serves as Senior Director of the global Centre for International Sustainable Development Law (CISDL). Having assisted in drafting the Paris Agreement, she has published over 24 books and 160 papers with world-class presses, edited five law journals and a Cambridge University Press book series, advised the United Nations and key countries, and helps purpose-led companies to advance the UN Sustainable Development Goals. 

Jeff Skopek headshot about
Jeff Skopek
University of Cambridge
Advisor
Jeff Skopek
University of Cambridge
Jeff Skopek headshot about

Jeff Skopek is an Associate Professor of Law at the University of Cambridge and Deputy Director of its Centre for Law, Medicine and Life Sciences. His research explores the normative and conceptual foundations of health law, focusing in particular on controversies about what harms and benefits count. Before coming to Cambridge, he was an Academic Fellow at Harvard Law School’s Petrie-Flom Centre for Health Law Policy, Biotechnology, and Bioethics. Prior to that, he served as a law clerk to Chief Judge Lynch of the United States Court of Appeals for the First Circuit. He holds an A.B. in History from Stanford University, a Ph.D. in the History and Philosophy of Science from the University of Cambridge, and a J.D. from Harvard Law School

Our values

Purposeful
We are aware of our own purpose. Our individual purpose is aligned to that of bit.bio: coding biology for the benefit of humanity. We look beyond our daily struggles, putting purpose first.
Ambitious
We are exceptionally driven and ambitious in the pursuit of our common goals and create things that have value. We get things done. Together we will change the world.
Collaborative & trustworthy
Our joint purpose and mission critically depend on bringing together our combined knowledge and skills. We value diversity and approach everyone with an open mind.
Empirical
We adhere to the scientific method. We put facts above opinions. In the absence of data, we create it. We know that the world is full of opportunities. Our mindset is one of abundance.

"At bit.bio, we are passionate about engineering human cells that will enable the medicine of the future."

Mark Kotter | MD, PhD, Founder 

Mark-Kotter-image

Related pages

News Read our latest updates and press coverage
Blog Learn more about cells, our products, company and culture
Our platform Discover the cell coding platform behind our cells