Highly consistent and scalable supply of lab grown human skeletal muscle cells provide an effective and biologically relevant tool for research and drug development in conditions as diverse as metabolic and muscle diseases and ageing.
CAMBRIDGE, Friday 15 October 2021 — bit.bio has today launched a new product, ioSkeletal Myocytes. It’s the first product of its kind that provides physiologically relevant human skeletal muscle cells that are reliable, reproducible and consistent at scale. Access to ioSkeletal Myocytes will supercharge research and drug discovery for musculoskeletal and metabolic conditions.
ioSkeletal Myocytes can be used within days after thawing, affording scientists unprecedented ease and consistency for their experiments. ioSkeletal Myocytes are created through direct reprogramming of human iPSCs (induced pluripotent stem cells) using bit.bio’s breakthrough cell coding technology opti-ox™. They are the second ‘off the shelf’ cell type product from bit.bio and form part of the expanding ioCells portfolio.
CEO and Founder | bit.bio
ioSkeletal Myocytes have been validated by bit.bio’s partners in different applications, a key stage in the development of the product. One partner, Charles River Laboratories, a provider of products and services that help expedite the discovery, early-stage development and safe manufacture of novel drugs and therapeutics, has adopted bit.bio’s ioSkeletal Myocytes into its discovery offering, including high-throughput screening (HTS) workflows.
Head of Biology - Leiden & Beerse | Charles River Laboratories
The product provides functional and consistent human cells which can be used to study the physiology of human skeletal muscle cells and their response to potential drug candidates.
bit.bio’s human ioSkeletal Myocytes will increase translatability of research findings so can play a significant role in reducing the average cost and time spent on drug development and increase the chances of new treatments making it through the clinic and to patients.
ioSkeletal Myocytes are launching ahead of a bit.bio workshop at The European Laboratory Research & Innovation Group (ELRIG) drug discovery conference where speakers Dr Luckshman Jeremy Anton (Charles River Laboratories), Prof Michael Duchen (University College London) and Prof Hagan Bayley (University of Oxford) will discuss the challenges of cell models and novel approaches and tools for basic research and drug discovery that include bit.bio’s cells.
ioSkeletal Myocytes are available through bit.bio and affiliated distributions to the greater academic and biotech communities.